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Overview
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Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
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- Properties
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Overview
Immunofluorescence analysis of MCF-7 cells using GYPC antibody (STJ23898). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using GYPC antibody (STJ23898) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-GYPC antibody
Anti-GYPC antibody
Catalog Number:
A001034065STJ
Mfr. No.:
STJ23898
Price:
$297
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