Name: Anti-Glycoprotein 1 of Seoul virus (SEOV). IgG fraction monoclonal antibody. Clone 2C8/B11
Price: 878.00 USD

- Overview
  - Mouse monoclonal antibody IgG fraction (clone 2C8/B11) obtained by immunizing mice with purified recombinant SEOV Glycoprotein 1 (G1). The IgG fraction was purified using Protein G-Sepharose.
    
    Please contact us at for specific academic pricing.
- Properties
  - Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Formulation
    
    Solution at 1.0 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
    
    Storage
    
    Store at -20°C.
    
    * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.
- Applications
  - Application Description
    
    This antibody can be used in ELISA (1:10,000 dilution) and Western blot (1:20,000 dilution) analysis. It recognizes specifically G1 glycoprotein of SEOV. Hantaviruses (family Bunyaviridae) are enveloped viruses that contain a tripartite, negative-stranded RNA genome encoding an RNA-dependent RNA polymerase (L), two integral membrane glycoproteins (G1 and G2), and a nucleocapsid (N) protein. The G1 and G2 glycoproteins form heterodimers and they attach the virion to a cell receptor and to promote fusion membrane after endocytosis of the virion. G1 can dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis. SEOV is a hantavirus causing a mild to moderate form of hemorrhagic fever with renal syndrome that is distributed mainly in Asia and Europe. It is transmitted by the rodents Rattus rattus and Rattus norvegicus.
- Reference
  - Zhang, Y-Z et al. (2009) Emerg. Infect. Dis. 15, 200-206.
    Lokugamage, N. et al. (2004) Microbiol. Immunol. 48, 843-851.
    Kim, Y.S. et al. (1995) Nephon 71, 419-427.
    Antic, D. et al. (1991) Virus Res. 19, 47-58.
    Arikawa, J. et al. (1990) Virology 176, 114-125.

Anti-Glycoprotein 1 of Seoul virus (SEOV). IgG fraction monoclonal antibody. Clone 2C8/B11

Anti-Glycoprotein 1 of Seoul virus (SEOV). IgG fraction monoclonal antibody. Clone 2C8/B11

We Also Recommend

anti-AAV VP1 mouse monoclonal, A1, lyophilized, purified

anti-AAV VP1/VP2 mouse monoclonal, A69, lyophilized, purified

Anti-AAV VP1/VP2/VP3 mouse monoclonal, B1, AFDyeTM 488 Conjugate