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Overview
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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and-independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Overview
Immunofluorescence analysis of A549 cells using GADD45A antibody (STJ115448).
Anti-GADD45A antibody
Anti-GADD45A antibody
Catalog Number:
A001022343STJ
Mfr. No.:
STJ115448
Price:
$297
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