Western blot analysis of extracts of rat liver, using FGF4 antibody (STJ116931) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s.

Anti-FGF4 antibody

Catalog Number:

A001023780STJ

Mfr. No.:

STJ116931

Price:

$297

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Overview
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 31-206 of human FGF4 (NP_001998. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Fibroblast Growth Factor 4; Fgf-4; Heparin Secretory-Transforming Protein 1; Hst; Hst-1; Hstf-1; Heparin-Binding Growth Factor 4; Hbgf-4; Transforming Protein Ks3 (Gene ID:2249; UniProt:P08620)
  
  * For research use only