Anti-FAP antibody

Catalog Number:

A001036531STJ

Mfr. No.:

STJ28432

Price:

$297

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Overview
- The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 26-280 of human FAP (NP_004451. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Prolyl Endopeptidase Fap; 170 Kda Melanoma Membrane-Bound Gelatinase; Dipeptidyl Peptidase Fap; Fibroblast Activation Protein Alpha; Fapalpha; Gelatine Degradation Protease Fap; Integral Membrane Serine Protease; Post-Proline Cleaving Enzyme; Serine Integral Membrane Protease; Simp; Surface-Expressed Protease; Seprase Cleaved Into-Antiplasmin-Cleaving Enzyme Fap-Soluble Form; Apce (Gene ID:2191; UniProt:Q12884)
  
  * For research use only