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Overview
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This gene encodes a member of the metallo beta-lactamase family of iron-containing proteins involved in the mitochondrial sulfide oxidation pathway. The encoded protein catalyzes the oxidation of a persulfide substrate to sulfite. Certain mutations in this gene cause ethylmalonic encephalopathy, an infantile metabolic disorder affecting the brain, gastrointestinal tract and peripheral vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
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- Properties
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Overview
Immunofluorescence analysis of U-2 OS cells using ETHE1 Polyclonal Antibody (STJ112181) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human colon carcinoma using ETHE1 antibody (STJ112181) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using ETHE1 antibody (STJ112181) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using ETHE1 antibody (STJ112181) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-ETHE1 antibody
Anti-ETHE1 antibody
Catalog Number:
A001019943STJ
Mfr. No.:
STJ112181
Price:
$297
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