Anti-ERCC4 antibody

Catalog Number:

A001017246STJ

Mfr. No.:

STJ110418

Price:

$297

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Overview
- The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthetic peptide corresponding to a sequence within amino acids 600-700 of human ERCC4 (NP_005227. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dna Repair Endonuclease Xpf; Dna Excision Repair Protein Ercc-4; Dna Repair Protein Complementing Xp-F Cells; Xeroderma Pigmentosum Group F-Complementing Protein (Gene ID:2072; UniProt:Q92889)
  
  * For research use only