Anti-ERCC3 antibody

Catalog Number:

A001021528STJ

Mfr. No.:

STJ114575

Price:

$297

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Overview
- This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 512-782 of human ERCC3 (NP_000113. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  General Transcription And Dna Repair Factor IIh Helicase Subunit Xpb; TfIIh Subunit Xpb; Basic Transcription Factor 2 89 Kda Subunit; Btf2 P89; Dna Excision Repair Protein Ercc-3; Dna Repair Protein Complementing Xp-B Cells; TfIIh Basal Transcription Factor Complex 89 Kda Subunit; TfIIh 89 Kda Subunit; TfIIh P89; Xeroderma Pigmentosum Group B-Complementing Protein (Gene ID:2071; UniProt:P19447)
  
  * For research use only