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Overview
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This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunoprecipitation analysis of 200ug extracts of MCF-7 cells using 3ug E2F6 antibody (STJ116186). Western blot was performed from the immunoprecipitate using E2F6 antibody (STJ116186) at a dilition of 1:500.
Immunofluorescence analysis of U2OS cells using E2F6 antibody (STJ116186). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human esophageal cancer using E2F6 antibody (STJ116186) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using E2F6 antibody (STJ116186) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of MCF-7 cells, using E2F6 antibody (STJ116186) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-E2F6 antibody
Anti-E2F6 antibody
Catalog Number:
A001023054STJ
Mfr. No.:
STJ116186
Price:
$297
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