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Overview
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Reacts with E-selectin CD62-E, previous designated the Endothelial Leucocyte AdhesionMolecule-1 (ELAM-1). The antibody reacts with human endothelial cells activated with TNF-alpha, IL-1 orendotoxin. The antibody was found to react also with cells transfected with the E-selectin gene. Theantibody inhibits the adhesion of granulocytes both neutrophilic and eosinophilic.
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