Anti-DYNLT1 antibody

Anti-DYNLT1 antibody

Catalog Number:
A001033801STJ
Mfr. No.:
STJ23453
Price:
$297
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      • Overview
        • This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1 (NP_006510. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Dynein Light Chain Tctex-Type 1; Protein Cw-1; T-Complex Testis-Specific Protein 1 Homolog (Gene ID:6993; UniProt:P63172)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:2000

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