Anti-DYNLRB1 antibody

Catalog Number:

A001024236STJ

Mfr. No.:

STJ117391

Price:

$297

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Overview
- This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dynein Light Chain Roadblock-Type 1; Bithoraxoid-Like Protein; Blp; Dynein Light Chain 2a-Cytoplasmic; Dynein-Associated Protein Km23; Roadblock Domain-Containing Protein 1 (Gene ID:83658; UniProt:Q9NP97)
  
  * For research use only