-
-
Overview
-
This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
Western blot analysis of extracts of various cell lines, using DYNC2LI1 antibody (STJ26842) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.
Anti-DYNC2LI1 antibody
Anti-DYNC2LI1 antibody
Catalog Number:
A001035583STJ
Mfr. No.:
STJ26842
Price:
$297
Size:
Quantity:
Add to Cart:
.