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Overview
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This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
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Overview
Immunofluorescence analysis of NIH/3T3 cells using DVL2 antibody (STJ29689) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse heart using DVL2 antibody (STJ29689) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using DVL2 antibody (STJ29689) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using DVL2 antibody (STJ29689) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using DVL2 Antibody (STJ29689) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-DVL2 antibody
Anti-DVL2 antibody
Catalog Number:
A001037646STJ
Mfr. No.:
STJ29689
Price:
$297
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