Name: Anti-DRP1 antibody
Price: 224.00 USD

Overview
- DRP1 is a protein encoded by the DNM1L gene which is approximately 81, 8 kDa. DRP1 is localised to the cytoplasm and Golgi apparatus. It is involved in toll-like receptor signalling pathways, the TNF signalling pathway, cytoskeletal signalling and apoptotic cleavage of cellular proteins. This protein falls under the dynamin superfamily of GTPases. It mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. DRP1 is expressed ubiquitously with the highest levels found in skeletal muscles, heart, kidney and brain. Mutations in the DNM1L gene may result in encephalopathy. STJ92779 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of DRP1 protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human DRP1 around the non-phosphorylation site of S637.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Dynamin-1-like protein; Dnm1p/Vps1p-like protein; DVLP; Dynamin family member proline-rich carboxyl-terminal domain less; Dymple; Dynamin-like protein; Dynamin-like protein 4; Dynamin-like protein IV; HdynIV; D (Gene ID:10059; UniProt:O00429)
  
  * For research use only