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Overview
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This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo-and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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- Properties
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Overview
Western blot analysis of extracts from normal (control) and DPYSL2 knockout (KO) HeLa cells, using DPYSL2 antibody (STJ116781) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.
Western blot analysis of extracts of various cell lines, using DPYSL2 antibody (STJ116781) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-DPYSL2 antibody
Anti-DPYSL2 antibody
Catalog Number:
A001023634STJ
Mfr. No.:
STJ116781
Price:
$295
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