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Overview
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This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.
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Overview
Immunofluorescence analysis of U2OS cells using DHRS9 antibody (STJ28246). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse brain using DHRS9 Antibody (STJ28246) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using DHRS9 antibody (STJ28246) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 60s.
Immunohistochemistry of paraffin-embedded rat brain using DHRS9 Antibody (STJ28246) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using DHRS9 antibody (STJ28246) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit._Exposure time: 390s.
Anti-DHRS9 antibody
Anti-DHRS9 antibody
Catalog Number:
A001036358STJ
Mfr. No.:
STJ28246
Price:
$297
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