Anti-DCAMKL2 antibody

Catalog Number:

A001048034STJ

Mfr. No.:

STJ92663

Price:

$224

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Overview
- DCAMKL2 is a protein encoded by the DCLK2 gene which is approximately 83, 6 kDa. DCAMKL2 is localised to the cytoplasm and is involved in transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. This protein falls under the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization. It also contains a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase. DCAMKL2 is expressed in the brain, heart and eye. The absence of this protein results in a severe epileptic phenotype and lethality. STJ92663 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of DCAMKL2 protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Synthesized peptide derived from human DCAMKL2
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Serine/Threonine-Protein Kinase Dclk2; Camk-Like Creb Regulatory Kinase 2; Cl2; Click-II; Click2; Doublecortin Domain-Containing Protein 3b; Doublecortin-Like And Cam Kinase-Like 2; Doublecortin-Like Kinase 2 (Gene ID:166614; UniProt:Q8N568)
  
  * For research use only