Anti-DAPK3 antibody

Catalog Number:

A001048025STJ

Mfr. No.:

STJ92654

Price:

$224

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Overview
- DAPK3 is a protein encoded by the DAPK3 gene which is approximately 52, 5 kDa. DAPK3 is localised to the nucleus and cytoplasm. It is involved in CDK-mediated phosphorylation and removal of Cdc6, dimerization of procaspase and pathways in cancer. It is a serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. It also plays a role in the regulation of smooth muscle contraction. DAPK3 is widely expressed in human tissues including the smooth muscle of the bladder. STJ92654 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of DAPK3 protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human DAPK3 around the non-phosphorylation site of T265.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Death-Associated Protein Kinase 3; Dap Kinase 3; Dap-Like Kinase; Dlk; Mypt1 Kinase; Zipper-Interacting Protein Kinase; Zip-Kinase (Gene ID:1613; UniProt:O43293)
  
  * For research use only