Anti-DAD1 antibody

Anti-DAD1 antibody

Catalog Number:
A001023772STJ
Mfr. No.:
STJ116923
Price:
$297
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      • Overview
        • DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DAD1 (NP_001335. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit Dad1; Oligosaccharyl Transferase Subunit Dad1; Defender Against Cell Death 1; Dad-1 (Gene ID:1603; UniProt:P61803)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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