Anti-CYP11B2 antibody

Catalog Number:

A001018971STJ

Mfr. No.:

STJ111090

Price:

$297

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Overview
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B2 (NP_000489. 3).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Cytochrome P450 11b2-Mitochondrial; Aldosterone Synthase; Aldos; Aldosterone-Synthesizing Enzyme; Cypxib2; Corticosterone 18-Monooxygenase-Cyp11b2; Cytochrome P-450aldo; Cytochrome P-450c18; Steroid 11-Beta-Hydroxylase-Cyp11b2; Steroid 18-Hydroxylase (Gene ID:1585; UniProt:P19099)
  
  * For research use only