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Overview
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Cyclin D1 or PRAD‐1 or bcl‐1 is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. It is a putative proto‐ oncogene over expressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).
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- Properties
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Overview