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Overview
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This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded rat brain using CRHR1 antibody (STJ110707) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using CRHR1 antibody (STJ110707) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CRHR1 antibody (STJ110707) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 20s.
Anti-CRHR1 antibody
Anti-CRHR1 antibody
Catalog Number:
A001017460STJ
Mfr. No.:
STJ110707
Price:
$297
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