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Overview
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The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded Human colon carcinoma using CPT1A Rabbit pAb (STJ27260) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CPT1A antibody (STJ27260) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-CPT1A antibody
Anti-CPT1A antibody
Catalog Number:
A001035733STJ
Mfr. No.:
STJ27260
Price:
$297
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