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Overview
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human stomach using CLDN3 antibody (STJ23159) (40x lens).
Immunohistochemistry of paraffin-embedded mouse stomach using CLDN3 antibody (STJ23159) (40x lens).
Immunohistochemistry of paraffin-embedded human colon using CLDN3 antibody (STJ23159) (40x lens).
Western blot analysis of extracts of various cell lines, using CLDN3 antibody (STJ23159) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-CLDN3 antibody
Anti-CLDN3 antibody
Catalog Number:
A001033627STJ
Mfr. No.:
STJ23159
Price:
$297
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