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Overview
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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
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Overview
Immunofluorescence analysis of MCF-7 cells using CHRM2 antibody (STJ23131). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using CHRM2 antibody (STJ23131) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-CHRM2 antibody
Anti-CHRM2 antibody
Catalog Number:
A001033607STJ
Mfr. No.:
STJ23131
Price:
$297
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