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Overview
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Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Overview
Immunohistochemistry of paraffin-embedded Human colon using CELF1 Rabbit pAb (STJ29928) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using CELF1 Rabbit pAb (STJ29928) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat brain using CELF1 Rabbit pAb (STJ29928) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CELF1 antibody (STJ29928) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 60s.
Anti-CELF1 antibody
Anti-CELF1 antibody
Catalog Number:
A001037812STJ
Mfr. No.:
STJ29928
Price:
$297
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