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Overview
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Human CD97 antigen, expressed mainly on myeloid cells and activated lymphocytes; 74-89 kDa. CD97antigen is a protein that in humans is encoded by the CD97 gene. This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene clusteron the short arm of chromosome 19. The encoded product is a glycoprotein that is present on thesurface of most activated leukocytes and spans the membrane seven times, which is a definingfeature of G protein-coupled receptors. The protein has an extended extracellular region with severalN-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade.Immunogen: PHA-activated peripheral blood cells
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Overview