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Overview
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CD90 (Thy-1) is an 18-35 kDa GPI-anchored glycoprotein and a member of the immunoglobulinsuperfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stemcells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids;25-35 kDa) inserted into the cell membrane via a GPI-anchor. Expressed by hematopoietic stem cellsand neurons in all species studied. Its highly expressed in connective tissue and various fibroblastsand stromal cell lines, expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bonemarrow, and <1% of CD3+ and CD4+ lymphocytes in peripheral circulation. It is also expressed by alimited number of lymphoblastoid and leukemic cell lines.Immunogen: T-cell lymphoma cells
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Overview