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Overview
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded mouse spleen using CD8A Rabbit pAb (STJ114922) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat spleen using CD8A Rabbit pAb (STJ114922) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of mouse pancreas, using CD8A antibody (STJ114922) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.
Anti-CD8A antibody
Anti-CD8A antibody
Catalog Number:
A001021848STJ
Mfr. No.:
STJ114922
Price:
$297
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