Anti-CD74 antibody

Catalog Number:

A001036034STJ

Mfr. No.:

STJ27634

Price:

$297

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Overview
- The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (A beta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 73-232 of human CD74 (NP_004346. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Hla Class II Histocompatibility Antigen Gamma Chain; Hla-Dr Antigens-Associated Invariant Chain; Ia Antigen-Associated Invariant Chain; II; P33; Cd Antigen Cd74 Cleaved Into-Class-II-Associated Invariant Chain Peptide; Clip (Gene ID:972; UniProt:P04233)
  
  * For research use only