Name: Anti-CD64 antibody
Price: 842.00 USD

- Overview
  - Reacts with human CD64. This molecule serves as a high affinity receptor for IgG. Alsoknown as Fc gamma RI, this molecule is expressed on monocytes and macrophages.Immunogen: Rheumatoid synovial fluid cells and fibronectin purified human monocytes.CD64 is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity. It is more commonly known as Fc-gamma receptor 1 (Fc gamma RI). Afterbinding IgG, CD64 interacts with an accessory chain known as the common gamma chain ( gamma chain), whichpossesses an ITAM (immunoreceptor tyrosine-based activation motif) that is necessary for triggeringcellular activation.Structurally CD64 is composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, ahydrophobic transmembrane domain, and a short cytoplasmic tail.Immunogen: Human CD64
    
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- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human
    
    Clone
    
    10.1
    
    Immunogen
    
    Rheumatoid synovial fluid cells and fibronectin purified human monocytes. CD64 is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity. It is more commonly known as Fc-gamma receptor
    
    Conjugate
    
    PE
    
    Formulation
    
    0.5 ml purified antibody, conjugated to R-PE, in Phosphate Buffer Saline solution containing sucrose, 4-5 mg/ml BSA and 0.1% sodium azide.
    
    Storage
    
    Store antibody at 2-8°C until expiry. Avoid prolonged exposure to light.
    
    Concentration
    
    approximately 0.1 mg/ml
    
    Regulatory Status
    
    RUO
    
    * For research use only
- Applications
  - Application
    
    Flow Cytometry