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Overview
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Reacts with a protein determinant of CD45RB, a 180-240 kDa single chain type I membraneglycoprotein, variant of CD45 (CD45RB isoform). CD45RB is expressed on a subset of T lymphocytes, Blymphocytes, monocytes, macrophages, granulocytes and dendritic cells. The MEM-143 is thereforenot neuraminidase sensitive like most other anti-CD45RB antibodies (including standard antibodyMEM-55). The reactivity of the antibody MEM-143 can be blocked by a peptide including amino acids79-88.Immunogen: Human peripheral blood lymphocytes.
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