-
-
Overview
-
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and-zeta, and the T-cell receptor alpha/ beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Please contact us at for specific academic pricing.
-
- Properties
- Applications
-
Overview
Immunofluorescence analysis of RAW264.7 cells using CD3E Antigen antibody (STJ114289) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Jurkat cells using CD3E Antigen antibody (STJ114289) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse spleen using CD3E Antigen antibody (STJ114289) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse thymus using CD3E Antigen antibody (STJ114289) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using CD3E Antigen Antibody (STJ114289) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-CD3E antibody
Anti-CD3E antibody
Catalog Number:
A001021260STJ
Mfr. No.:
STJ114289
Price:
$297
Size:
Quantity:
Add to Cart:
.