Name: Anti-CD14/human monocyte antibody
Price: 632.00 USD

Overview
- Reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membraneglycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed bymost tissue macrophages. CD14 binds lipopolysaccharide molecule in a reaction catalyzed bylipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able todiscriminate slight structural differences between lipopolysaccharides and is important forneutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14affects allergic, inflammatory and infectious processes.Immunogen: mixture of human urinary proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  MEM-15
  
  Immunogen
  
  A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  100 µg of affinity purified antibody in PBS containing 15 mM sodium Azide, pH 7.4.: 1 mg/ml
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Monocyte Differentiation Antigen Cd14; Myeloid Cell-Specific Leucine-Rich Glycoprotein; Cd Antigen Cd14 Cleaved Into-Monocyte Differentiation Antigen Cd14-Urinary Form-Monocyte Differentiation Antigen Cd14-Membrane-Bound Form (Gene ID:929; UniProt:P08571)
  
  * For research use only