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Overview
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This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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- Properties
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Overview
Immunohistochemistry of paraffin-embedded human stomach using CBX1 antibody (STJ22919) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using CBX1 antibody (STJ22919) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of OVCAR-3 cells, using CBX1 antibody (STJ22919) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-CBX1 antibody
Anti-CBX1 antibody
Catalog Number:
A001033485STJ
Mfr. No.:
STJ22919
Price:
$297
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