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Overview
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This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
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- Properties
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Overview
Immunoprecipitation analysis of 100ug extracts of HepG2 cells using 3ug CAT antibody (STJ113364). Western blot was performed from the immunoprecipitate using CAT antibody (STJ113364) at a dilition of 1:1000.
Western blot analysis of extracts of various cell lines, using CAT antibody (STJ113364) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 5s.
Anti-CAT antibody
Anti-CAT antibody
Catalog Number:
A001020649STJ
Mfr. No.:
STJ113364
Price:
$297
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