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Overview
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C-peptide is produced when proinsulin is split into insulin and C-peptide. They split before proinsulin is released from endocytic vesicles within the pancreas-one C-peptide for each insulin molecule. When a patient has newly diagnosed type 1 or type 2 diabetes, C-peptide can be used to help determine how much insulin the patient’s pancreas is still producing. C-peptide measurements also can be used in conjunction with insulin and glucose levels to help diagnose the cause of documented hypoglycemia and to monitor its treatment.
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