Anti-Beta-Catenin antibody

Overview
- Beta-catenin is a 92 kD protein normally found in the cytoplasm of the cell in the submembranouslocation. Mutations in the beta-catenin gene result in nuclear accumulation of this protein. Nuclearaccumulation of this protein has been demonstrated in fibromatosis (desmoid tumors) of the breastand abdomen and, therefore, is useful in differentiating from other spindle cell neoplasms that mayoccur in these locations.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  14
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Catenin Beta-1; Beta-Catenin (Gene ID:1499; UniProt:P35222)
  
  * For research use only

Applications

Application	Dilutions
IHC	1:25-1:100