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Overview
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This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16.
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Overview
Immunofluorescence analysis of U2OS cells using BCAP31 antibody (STJ29136). Blue: DAPI for nuclear staining.
Immunoprecipitation analysis of 200ug extracts of HeLa cells, using 3 ug BCAP31 antibody (STJ29136). Western blot was performed from the immunoprecipitate using BCAP31 antibody (STJ29136) at a dilition of 1:1000.
Western blot analysis of extracts of various cell lines, using BCAP31 antibody (STJ29136) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-BCAP31 antibody
Anti-BCAP31 antibody
Catalog Number:
A001037162STJ
Mfr. No.:
STJ29136
Price:
$297
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