Anti-BAAT antibody

Catalog Number:

A001037839STJ

Mfr. No.:

STJ29960

Price:

$297

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Overview
- The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 309-418 of human BAAT (NP_001692. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Bile Acid-Coa-Amino Acid N-Acyltransferase; Bacat; Bat; Bile Acid-Coa Thioesterase; Choloyl-Coa Hydrolase; Glycine N-Choloyltransferase; Long-Chain Fatty-Acyl-Coa Hydrolase (Gene ID:570; UniProt:Q14032)
  
  * For research use only