Name: Anti-B4GALT2 antibody
Price: 297.00 USD

Overview
- This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 155-271 of human B4GALT2 (NP_085076. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Beta-1-4-Galactosyltransferase 2; Beta-1-4-Galtase 2; Beta4gal-T2; B4gal-T2; Beta-N-Acetylglucosaminyl-Glycolipid Beta-1-4-Galactosyltransferase; Beta-N-Acetylglucosaminylglycopeptide Beta-1-4-Galactosyltransferase; Lactose Synthase A Protein; N-Acetyllactosamine Synthase; Nal Synthase; Udp-Gal-Beta-Glcnac Beta-1-4-Galactosyltransferase 2; Udp-Galactose-Beta-N-Acetylglucosamine Beta-1-4-Galactosyltransferase 2 (Gene ID:8704; UniProt:O60909)
  
  * For research use only