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Overview
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Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
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Overview
Western Blot was carried out on SH-SY5Y lysates using Anti-ATXN3 polyclonal antibody at 1:500 dilution, with lysates of 100 µg per lane and secondary antibody rabbit anti-goat IgG (HRP) at 1:10,000 dilution.
Anti-ATXN3 antibody
Anti-ATXN3 antibody
Catalog Number:
A001027596STJ
Mfr. No.:
STJ140015
Price:
$250
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