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Overview
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Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2, 8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
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Overview
Immunofluorescence analysis of NIH/3T3 cells using APRT Rabbit pAb (STJ115881) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using APRT Rabbit pAb (STJ115881) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human prostate using APRT Antibody (STJ115881) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using APRT Antibody (STJ115881) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using APRT antibody (STJ115881) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-APRT antibody
Anti-APRT antibody
Catalog Number:
A001022759STJ
Mfr. No.:
STJ115881
Price:
$297
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