Name: Anti-Annexin A1 antibody
Price: 1006.00 USD

Overview
- Anaplastic lymphoma kinase (ALK) is a novel receptor protein-tyrosine kinase. ALK can create afusion protein with a nuclear protein gene called nucleophosmin (NPM) via the amino terminus ofNPM and the catalytic domain of ALK. The product of this fusion protein is oncogenic. Studies havefound this chromosomal translocation in most anaplastic large-cell non-Hodgkin's lymphomas, making ALK a good marker for anaplastic large cell lymphomas. ANXA1 is strongly expressed on thecell membrane and occasionally in the cytoplasm of tumour cells in 97% of samples from patientswith hairy cell leukaemia. By contrast, B-cell lymphomas other than hairy cell leukaemia, includingtypical splenic lymphoma with villous lymphocytes and patients with variant hairy cell leukaemiaîasdefined by current morphologic, phenotypic, and clinical criteriaîare ANXA1-negative.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human
  
  Clone
  
  MRQ-3
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
  
  Storage
  
  Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 Inhibitory Protein; P35 (Gene ID:301; UniProt:P04083)
  
  * For research use only