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Overview
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This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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Overview
Immunofluorescence analysis of HeLa cells using AK1 antibody (STJ22560). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human esophageal cancer using AK1 antibody (STJ22560) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using AK1 antibody (STJ22560) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using AK1 antibody (STJ22560) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Anti-AK1 antibody
Anti-AK1 antibody
Catalog Number:
A001033278STJ
Mfr. No.:
STJ22560
Price:
$297
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