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Overview
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This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
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- Properties
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Overview
Immunofluorescence analysis of HeLa cells using ADAR antibody (STJ110179) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded mouse spleen using ADAR antibody (STJ110179) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat spleen using ADAR antibody (STJ110179) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using ADAR antibody (STJ110179) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using ADAR Rabbit pAb (STJ110179) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.
Anti-ADAR antibody
Anti-ADAR antibody
Catalog Number:
A001017029STJ
Mfr. No.:
STJ110179
Price:
$297
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