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Overview
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The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
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- Properties
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Overview
Immunofluorescence analysis of HeLa cells using AAAS antibody (STJ28510). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using AAAS antibody (STJ28510) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.
Anti-AAAS antibody
Anti-AAAS antibody
Catalog Number:
A001036604STJ
Mfr. No.:
STJ28510
Price:
$297
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