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Overview
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Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
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Overview
Immunohistochemistry of paraffin-embedded mouse brain using A1CF antibody (STJ115054) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat ovary using A1CF antibody (STJ115054) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human tonsil using A1CF antibody (STJ115054) at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using A1CF antibody (STJ115054) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 1s.
Anti-A1CF antibody
Anti-A1CF antibody
Catalog Number:
A001021957STJ
Mfr. No.:
STJ115054
Price:
$297
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