Annexin V Apoptosis Detection Kit

- Overview
  - Annexin V Apoptosis Detection Kits are a convenient, easy-to-use and safe method for Apoptosis Detection. Annexins are a family of calcium-dependent phospholipid-binding proteins, which bind to phosphatidylserine (PS).
    
    Advantages & Features
    
    Easy and one step protocol: get results with few handling steps.
    
    Detection Method: Flow cytometry (Ex = 488 nm; Em = 530 nm) and fluorescence microscopy.
    
    Mammalian Reactivity.
    
    Proven performance for both adherent and suspension cells.
    
    Versatile: most used kits availables.
    
    Safe: non-enzymatic assay that avoids fixation.
    
    Risk-free: product covered by our Quality 100% Guarantee.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Cell Viability, Proliferation & Cytotoxicity Assays
    
    Storage
    
    All components should be stored at 4 °C. All components are stable for 2 years, if stored properly.
    
    Shipping
    
    Gel pack.
    
    * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.
- Applications
  - Application Description
    
    For a Convenient, Easy & Fast method for Apoptosis Detection by Flow Cytometry and Fluorescence Microscopy.
    Detect early/middle stages of Apoptosis.
    Differentiate apoptosis from necrosis.
- Reference
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    José, M., Grueso, L., María, R., Valero, T., Beatriz, C. H., Daniel, L. R., … & Alicia, P. C. (2019). Peroxiredoxin 6 Down-Regulation Induces Metabolic Remodeling and Cell Cycle Arrest in HepG2 Cells. Antioxidants, 8(11), 505.
    
    Luparello, C., Ragona, D., Asaro, D. M. L., Lazzara, V., Affranchi, F., Celi, M., … & Vazzana, M. (2019). Cytotoxic Potential of the Coelomic Fluid Extracted from the Sea Cucumber Holothuria tubulosa against Triple-Negative MDA-MB231 Breast Cancer Cells. Biology, 8(4), 76.
    
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    García-Pastor, C., Blázquez-Serra, R., Bosch, R. J., Cazaña, F. J. L., & Fernández-Martínez, A. B. (2019). Apoptosis and cell proliferation in proximal tubular cells exposed to apoptotic bodies. Novel pathophysiological implications in cisplatin-induced renal injury. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.
    
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    Luparello, C., Asaro, D. M. L., Cruciata, I., Hassell-Hart, S., Sansook, S., Spencer, J., & Caradonna, F. (2019). Cytotoxic Activity of the Histone Deacetylase 3-Selective Inhibitor Pojamide on MDA-MB-231 Triple-Negative Breast Cancer Cells. International Journal of Molecular Sciences, 20(4), 804.
    
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    Martínez-Valdivieso, D., Font, R., Fernández-Bedmar, Z., Merinas-Amo, T., Gómez, P., Alonso-Moraga, Á., & Del Río-Celestino, M. (2017). Role of Zucchini and Its Distinctive Components in the Modulation of Degenerative Processes: Genotoxicity, Antigenotoxicity, Cytotoxicity and Apoptotic Effects. Nutrients, 9(7), 755.